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New Study Finds Active Smoking Increases Risk of Breast Cancer [01/07-2]

Excerpts from: Active smoking associated with increased risk of breast cancer

EurekAlert
[01/06/04]


Active smoking appears to play a larger role in the development of breast cancer than previously thought, according to a study in the January 7 issue of the Journal of the National Cancer Institute.

Tobacco smoke contains a number of human carcinogens, and metabolites of cigarette smoke have been found in the breast fluid of smokers. However, studies examining the association between tobacco smoke and breast cancer risk have yielded inconsistent results. Many studies have not been able to independently assess the contributions of the timing of exposure, age of diagnosis, or genetic susceptibilities to the overall risk of breast cancer. In addition, many of these studies did not consider passive smoking exposures, or exposure to secondhand smoke, among nonsmokers.

Between 1996 and 2000, 2,005 of the women were diagnosed with invasive breast cancer. The incidence of breast cancer among current smokers was approximately 30% greater than that among women who had never smoked, irrespective of whether they were compared to women who had or had not been exposed to passive smoking. Analysis of subgroups of active smokers revealed increased breast cancer risks among women who started smoking before age 20, who began smoking at least 5 years before their first full-term pregnancy, and who had a longer duration of smoking or who smoked 20 or more cigarettes per day.

Current smoking was associated with increased breast cancer risk in women without a family history of breast cancer but not among women with a family history of the disease. There was no statistically significant increase in breast cancer risk among former smokers, and there was no evidence of an association between passive smoking exposure and breast cancer risk.

Click Here to View the Abstract of this Study


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